In addition to its powerful gel-based protein and proteome services NHD offers sophisticated mass spectrometry (MS) services such as
- • Shot Gun MS for protein identifcation in proteomes
- • Targeted MS for ID and validation of biomarkers
- • MALDI-TOF fingerprinting
NHD mass spec services enables the detection, identification and quantification of proteins by measuring their mass and characterizing their chemical structure.
Mass spectrometry in proteomics
In proteomics, mass spectrometry is applied to characterize and sequence proteins. Over the last decades, it has become an indispensable technique. Its development over the last decades has led to three fundamental applications: determining protein interaction, categorizing protein expression and locating protein modification.
Mass spectrometry in pharmacology
In pharmacology, mass spectrometry is applied for drug discovery to determine the structure of drugs and metabolites and for screening metabolites in biological systems.
Tandem Mass Spectrometry (MS/MS)